Ozone IV Therapy
in Sterling, VA
At NOVA IV Therapy, we provide medically supervised ozone therapy within a structured clinical setting in Sterling, VA. Ozone-based procedures are offered as part of a provider-directed, integrative approach to care when appropriate.
Patients throughout Northern Virginia seek out ozone therapy for a variety of wellness and supportive care goals, particularly when exploring additional options beyond conventional approaches. Our focus is on safety, proper protocol, and individualized evaluation rather than one-size-fits-all treatment.
All ozone therapies are performed under licensed medical supervision using established procedures and calibrated medical equipment.
What is Ozone Therapy and How is it Used
Ozone therapy involves the use of a medical-grade oxygen–ozone mixture in a controlled medical environment. In intravenous ozone procedures, blood is withdrawn, exposed to the oxygen–ozone mixture outside the body, and then reinfused through a sterile system.
This extracorporeal process allows the interaction to occur outside the bloodstream. The ozone gas itself is not directly injected into circulation.
In integrative medicine settings, ozone therapy is studied and utilized for its potential role in influencing:
• Oxygen utilization
• Oxidative balance
• Circulatory dynamics
• Cellular signaling processes
Ozone does not function like a drug. Instead, it works as a biological response modifier. When ozone interacts with blood outside the body, it creates specific byproducts, often referred to as ozonides and peroxides. These byproducts act as signaling molecules that encourage the body to improve oxygen delivery, enhance antioxidant defenses, and regulate immune activity.
These effects are still being studied, and clinical use varies based on provider training, patient selection, and regional medical practices.
Ozone therapy is not a pharmaceutical intervention and is not approved by the FDA for the diagnosis or treatment of specific diseases.
Major Autohemotherapy (MAH):
The Foundation of Ozone Therapy
Major Autohemotherapy, commonly referred to as MAH, is the foundational method of medical ozone therapy and has been used internationally for decades in integrative medical settings.
During an MAH session:
• The patient is provided with a short-acting anti-coagulant to prevent blood-clotting, usually Heparin.
• Then a measured amount of the patient’s blood is withdrawn from a vein into a sterile IV bag.
• Medical-grade ozone is then infused into the bag and gently mixed with the blood (this is actually still 95% oxygen).
• After this external interaction occurs, the treated blood is transfused back through the patient’s vein.
Because the ozone reacts with the blood outside the body, pure ozone gas is not entering the bloodstream. Instead, the therapeutic effect comes from the biological byproducts created during the mixing process. These byproducts help enhance oxygen utilization, support detoxification, and stimulate immune system activity.
MAH is performed under provider supervision with appropriate screening and safety protocols in place
When Ozone Therapy May Be Considered
In integrative care settings, ozone therapy is sometimes explored as a supportive option within a broader care plan.
Patients may inquire about ozone therapy in the context of:
• General wellness and recovery goals
• Periods of increased physiological stress
• Circulatory or oxygenation-related concerns
• Immune system support considerations
• Long-standing or complex health challenges
Ozone procedures are not intended to diagnose, treat, cure, or prevent disease, and are not appropriate for every individual. A provider consultation is required to determine whether ozone therapy may be appropriate based on medical history and individual circumstances.
Ozone is not appropriate for everyone. It is not indicated in blood disorders, during the first 3 months of pregnancy, or in individuals with glucose-6-phosphate dehydrogenase deficiency (G6PD), a rare condition that is screened for prior to treatment.
10-Pass Ozone Therapy (High-Dose Ozone Therapy)
10-Pass ozone therapy, also known as high-dose ozone therapy or OHT, is a more intensive evolution of MAH. It builds upon the same foundational principles but repeats the process multiple times in a single session to achieve deeper systemic effects.
During a 10-Pass session:
• A small amount of blood is withdrawn into a sterile bottle,
• The blood is exposure to a calibrated oxygen–ozone mixture under controlled conditions
• Then it is reintegration into circulation
• The process is then repeated a total of 10 times within the same session.
• There are additional intensities of 15-pass and 20-pass that can be offered when appropriate.
What distinguishes 10-Pass therapy from standard MAH is both the cumulative ozone exposure and its impact on cellular signaling.
10-Pass therapy is more intensive than standard MAH and is only performed following appropriate evaluation and under strict medical supervision. Treatment planning is individualized, and patients are typically guided through a stepwise approach based on tolerance and response.
When 10-Pass Therapy is Considered
Higher-intensity ozone protocols, such as 10-Pass therapy, may be discussed in cases where patients are seeking more structured or progressive supportive care options.
This may include individuals:
• Exploring integrative approaches for complex health concerns
• Seeking additional support after initial MAH sessions
• Looking for a more intensive protocol under provider supervision
All decisions regarding progression of therapy are made based on individual response, safety considerations, and provider clinical judgment.
Hemealumen Light Therapy (Adjunctive)
Hemealumen is an adjunctive therapy that may be used alongside IV and ozone-based procedures. It utilizes controlled light exposure across multiple wavelengths in an extracorporeal system.
Wavelengths of Light include:
• Infrared (800nm)
• Dual Red LEDs (625 and 660 nm)
• Green LED (525 nm)
• Violet LED (430 nm)
• Ultraviolet A (340, 365 nm)
• Ultraviolet C (253.7 nm)
In clinical and research settings, light-based therapies are studied for their interaction with cellular processes, including mitochondrial activity and blood components.
When used in conjunction with ozone therapy, Hemealumen is applied within a controlled protocol under provider supervision.
As with all services offered at NOVA IV Therapy, this therapy is discussed in detail during consultation to determine appropriateness.
Integrating Ozone Therapy Within a Broader Care Approach
At NOVA IV Therapy, ozone therapy is not used in isolation. It is considered as part of a broader, provider-directed approach that may also include nutrition, lifestyle considerations, and other supportive therapies when appropriate.
Depending on individual circumstances, ozone-based procedures may be combined with IV nutrient therapies such as glutathione or hydration support. All recommendations are made following a provider consultation and are tailored to the patient’s health history, goals, and overall care plan.
This integrative approach focuses on thoughtful, individualized care rather than reliance on a single intervention.
Proudly Serving the D.C., Maryland, Virginia Metro Region
NOVA IV Therapy is conveniently located off Route 7 in Loudoun County, making it easily accessible for patients throughout Sterling, Ashburn, Reston, Herndon, Tyson's, Leesburg and the surrounding areas. Designed with comfort and healing in mind, our space allows us to make functional medicine, and IV therapies available in one cohesive environment.
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NOVA IV Therapy welcomes patients from Washington D.C. and Virginia, including but not limited to: Arlington, Alexandria, Falls Church, Fairfax, Vienna, McLean, Tysons, Reston, Leesburg, Manassas, Manassas Park, Springfield, Woodbridge, Dale City Herndon, Sterling, Ashburn, Gainesville, Haymarket, Aldie, South Riding, Chantilly, Centreville, Clifton, Burke, Fairfax Station, Great Falls, Oakton, Leesburg, Purcellville, Middleburg, Winchester, Round Hill, Hamilton, Lovettsville, Bluemont, Brambleton, Broadlands.
NOVA IV Therapy welcomes patients from Maryland, including but not limited to: Silver Spring, Bethesda, Rockville, Gaithersburg, Germantown, Columbia, and Bowie, Potomac, North Potomac, Point of Rocks, Darnestown, Poolesville, Frederick, Chevy Chase, Ellicott City.
REFERERNCES DISCLAIMER:
NOVA IV Therapy provides links to the articles for educational purposes. The information contained in these publications were obtained from sources believed to be reliable and based on real scientific information from experienced researchers. While NOVA IV Therapy offers these references to its patients, their utilization is purely voluntary and not binding. NOVA IV Therapy makes no guarantee of results and assumes no liability or responsibility in connection with the references provided.
NOVA IV Therapy has no control whatsoever in regards to performance or non-performance, misinterpretation, proper or improper the use of information or suggestions contained in these publications by any person or entity. NOVA IV Therapy expressly disclaims any liability in connection thereto. Publications are subject to periodic reviews or revisions and readers are cautioned to obtain latest editions.
References and Clinical Studies for Ozone IV Therapy
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Efficacy of ozone adjuvant therapy in COVID-19 patients: A meta-analysis study
https://pubmed.ncbi.nlm.nih.gov/36438064/
Ozone high dose therapy (OHT) improves mitochondrial bioenergetics in peripheral blood mononuclear cellshttps://pubmed.ncbi.nlm.nih.gov/35880042/
A pilot randomized controlled trial of major ozone autohemotherapy for patients with post-acute sequelae of COVID-19https://pubmed.ncbi.nlm.nih.gov/39018686/
Ozone and oxidation therapies as a solution to the emerging crisis in infectious disease management: a review of current knowledge and experiencehttps://pubmed.ncbi.nlm.nih.gov/31898609/
Ozone dialysis delivers three or more times the ozone than other forms of ozone blood treatmenthttps://pubmed.ncbi.nlm.nih.gov/36204785/
Ozone therapy as a primary and sole treatment for acute bacterial infection: case reporthttps://pubmed.ncbi.nlm.nih.gov/30319768/
Ozone high dose therapy (OHT) improves mitochondrial bioenergetics in peripheral blood mononuclear cellshttps://pubmed.ncbi.nlm.nih.gov/35880042/
Ozone: a natural bioactive molecule with antioxidant property as potential new strategy in aging and in neurodegenerative disordershttps://pubmed.ncbi.nlm.nih.gov/32810649/
The Mito-Hormetic Mechanisms of Ozone in the Clearance of SARS-CoV2 and in the COVID-19 Therapyhttps://pubmed.ncbi.nlm.nih.gov/36140358/
Ozone therapy in 65 patients with fibromyalgia: an effective therapyhttps://pubmed.ncbi.nlm.nih.gov/30840304/
Medical Ozone Increases Methotrexate Effects in Rheumatoid Arthritis Through a Shared New Mechanism Which Involves Adenosinehttps://pubmed.ncbi.nlm.nih.gov/40508064/
Medical Ozone: A Redox Regulator with Selectivity for Rheumatoid Arthritis Patientshttps://pubmed.ncbi.nlm.nih.gov/38543177/
Ozone alleviates MSU-induced acute gout pain via upregulating AMPK/GAS6/MerTK/SOCS3 signaling pathwayhttps://pubmed.ncbi.nlm.nih.gov/38066599/
Effect of Ozone in Freund's Complete Adjuvant-Induced Arthritishttps://pubmed.ncbi.nlm.nih.gov/30207561/
Anti-inflammatory Effect of Ozone Therapy in an Experimental Model of Rheumatoid Arthritishttps://pubmed.ncbi.nlm.nih.gov/32382842/
Ozone therapy: an overview of pharmacodynamics, current research, and clinical utilityhttps://pubmed.ncbi.nlm.nih.gov/29152215/
The Protective Role of Ozone Therapy in Kidney Disease: A Reviewhttps://pubmed.ncbi.nlm.nih.gov/36983907/
Oxygen-ozone therapy for myocardial ischemic stroke and cardiovascular disordershttps://pubmed.ncbi.nlm.nih.gov/39217427/
The possibilities of using the effects of ozone therapy in neurologyhttps://pubmed.ncbi.nlm.nih.gov/33932964/
Oxygen-Ozone (O2-O3) Therapy in Peripheral Arterial Disease (PAD): A Review Studyhttps://pubmed.ncbi.nlm.nih.gov/32636631/
Efficacy of two doses of intra-articular ozone therapy for pain and functional mobility in knee osteoarthritis: a double-blind randomized trialhttps://link.springer.com/article/10.1186/s42358-025-00443-w
Randomised, double-blinded, placebo-controlled, clinical trial of ozone therapy as treatment of sudden sensorineural hearing loss
Frequently Asked Questions
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Ozone therapy involves the use of a medical-grade oxygen–ozone mixture in a controlled clinical setting. In IV applications, blood is exposed to this mixture outside the body and then reinfused under medical supervision.
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No. Ozone is never injected directly into veins or arteries. It is mixed with blood outside the body and then reinfused.
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MAH is a single-cycle ozone procedure, while 10-Pass therapy involves repeating the process multiple times during one session. The difference primarily relates to the total volume of blood treated and overall treatment duration. All approaches are determined based on provider evaluation and patient-specific considerations.
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When performed by trained medical professionals using appropriate protocols and patient screening, ozone therapy is generally well tolerated. As with any procedure, risks and suitability are reviewed during consultation.
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Single Pass MAH: 45-60 minutes
Double Pass MAH: 60-75 minutes
5 Pass: 45-60 minutes
10-Pass: 60-75 minutes
EBOO: 90-120 minutes
Hemealumen Add-On to Ozone: 30-45 minutes more
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New patients can complete an intake through NOVA IV Therapy before starting treatment.
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Ozone therapy services are not currently covered by insurance. Payment is collected at the time of service.
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Yes, we do.
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Single-Pass MAH: $250
Double-Pass MAH: $300
Five-Pass: $600
Ten-Pass: $1000
EBOO Standard 3/5 Blood Volume (Ozone Dialysis): $1275
Hemealumen Stand-Alone (Single-Pass, 250cc): $400
Hemealumen Stand-Alone (Double-Pass, 500cc): $500
Hemealumen Add-On to Single-Pass MAH Ozone: $150
Hemealumen Add-On to Double-Pass MAH Ozone: $200
Hemealumen Add-On to 5-Pass Ozone: $250
Hemealumen Add-On to 10-Pass Ozone: $300
Hemealumen Add-On to EBOO: $300
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Ozone insufflation therapy is a non-invasive treatment that introduces ozone into the body via specific targeted areas.
Available Ozone Insufflation Treatments include:
Ear Insufflation (For Sinus Infections): $35
Vaginal Insufflation (For Yeast Infections): $35
Rectal Insufflation (For Colon and Liver Infections): $35
Medical & Regulatory Disclaimer
Nutrient IV therapies and ozone-based therapies, including Major Autohemotherapy (MAH), 10-Pass, Extracorporeal Blood Oxygenation and Ozonation (EBOO), and use of the Hemealumen device, are elective wellness services offered under the clinical judgment of licensed providers.
These therapies and protocols are not approved by the U.S. Food and Drug Administration (FDA) for the diagnosis, treatment, cure, or prevention of any disease or medical condition. Statements regarding these services have not been evaluated by the FDA.
These services may be described as investigational, adjunctive, or alternative in nature. No claims are made regarding therapeutic outcomes, efficacy, or specific health benefits, and individual results may vary.
The information provided on this website is for general educational and informational purposes only and is not intended as medical advice. Use of this website does not create a provider–patient relationship. Clinical decisions and medical advice are provided only in the context of an in-person consultation with a licensed healthcare professional.
All medical procedures carry inherent risks. You are responsible for discussing potential risks, benefits, contraindications, and alternatives with a qualified healthcare provider before electing to pursue any service.

